Anti-U3 ribonucleoprotein antibody-positive inflammatory myopathy: a case report
نویسندگان
چکیده
منابع مشابه
Anti-U3 ribonucleoprotein antibody-positive inflammatory myopathy: a case report
BACKGROUND The discovery of myositis-specific autoantibodies and myositis-associated autoantibodies has led to a new serological classification. Human U3 RNP, which consists of the U3 small nucleolar RNA and anti-U3 RNP antibody, is directed against one of the subunits. Anti-U3 RNP antibodies have been detected in 5-8 % of patients with systemic sclerosis, and antibody-positive patients with sy...
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OBJECTIVE The HLA 8.1 ancestral haplotype (HLA-B*08/DRB1*03/DQA1*05/DQB1*02) is associated with adult/juvenile idiopathic inflammatory myopathy (IIM), but confers a greater strength of association in patients possessing anti-Jo-1 or anti-PM-Scl antibodies. The HLA-DPB1 gene is centromeric to other HLA class II loci and separated by a recombination hotspot. We investigated whether HLA-DPB1 assoc...
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ژورنال
عنوان ژورنال: Journal of Medical Case Reports
سال: 2016
ISSN: 1752-1947
DOI: 10.1186/s13256-016-0941-4